Testosterone Replacement Therapy And Fertility  Testosterone Replacement Therapy And Fertility 



Testosterone Replacement Therapy And Fertility 


Testosterone Replacement Therapy (TRT) can lower fertility by signalling the testicles to shut down when external testosterone is introduced. Fortunately, Human Chorionic Gonadotropin (HCG) can mimic these signals, prompting the testicles to keep functioning normally, producing semen and testosterone, and maintaining their size. In rare instances where HCG is ineffective, Human Menopausal Gonadotropin (HMG) can be a more potent fertility treatment. Monitoring fertility during TRT is crucial. Androgenix offers HCG to suitable candidates on TRT to safeguard fertility.

Do You Have the Features of Testosterone Deficiency?

The Androgen Deficiency in Aging Males (ADAM) questionnaire is an easy way to answer questions about your sexual health, which can help to see if you need your testosterone level checked.

It is an internationally accredited assessment tool which is often used by doctors when making the assessment and diagnosis of Testosterone Deficiency.  A positive result does not necessarily mean that you have a low testosterone level or require treatment, but can be a helpful guide when discussing your symptoms with your doctor.

ADAM Questionnaire

Please answer the questions below.

Step of

1. Do you have a decrease in libido (sex drive)?

2. Do you have a lack of energy?

3. Do you have a decrease in strength and/or endurance?

4. Have you lost height?

5. Have you noticed a decreased "enjoyment of life"?

6. Are you sad and/or grumpy?

7. Are your erections less strong?

8. Have you noticed a recent deterioration in your ability to play sports?

9. Are you falling asleep after dinner?

10. Has there been a recent deterioration in your work performance?

You may have Testosterone Deficiency. We would recommend a consultation with our experts to discuss a treatment

Sex assigned at Birth (i) *



TRT With Fertility - Striking A Balance Between Both


Are you considering Testosterone Replacement Therapy (TRT) but concerned about future fertility aspirations? While common belief suggests TRT and fertility aren't compatible, is this notion accurate? Can you alleviate present symptoms with TRT while preserving fertility for future family planning?


Is TRT Truly Detrimental to Fertility? Discover Solutions to Preserve Your Reproductive Potential.


Before you give in to feelings of despair and settle into a life marked by irritability and sadness, continue reading for further insights and guidance on how to prevent infertility while undergoing Testosterone Replacement Therapy (TRT).



What’s The Role Of Testosterone In Fertility


Contrary to common belief, men with naturally low testosterone exhibit reduced sperm count and quality compared to their counterparts with normal or elevated testosterone levels. 


This might lead one to assume that testosterone replacement therapy (TRT) could be a panacea for fertility issues. 


However, the reality is more complex. Fertility and TRT share a delicate relationship, primarily because the testosterone vital for sperm production is endogenously synthesized within the testes and cannot be effectively substituted through TRT.


In a typical physiological process, the brain secretes gonadotropin-releasing hormones (GnRH), signalling the testes to ramp up testosterone production, essential for maintaining optimal sperm health. This intricate balance underscores the nuanced interplay between hormone therapy and male fertility, challenging the simplistic notion of using TRT as a straightforward solution for fertility enhancement.


Testosterone replacement therapy involves introducing testosterone into the bloodstream through various means, such as injections or gels. 


When this occurs, the brain perceives the increase in testosterone levels and assumes sufficient testosterone is present. Consequently, it reduces the signalling to the testes (via LH and FSH) to produce more testosterone.


With reduced stimulation from LH and FSH, the testes produce less testosterone, leading to a decline in sperm production and quality. 


Therefore, even lower doses of exogenous testosterone can negatively impact fertility, as any additional testosterone decreases the body's natural production and affects fertility levels.



Preserving Fertility During Testosterone Replacement Therapy


You have three options for maintaining while on testosterone replacement therapy:


1. Attempting To Conceive Anyway:


Even though testosterone replacement therapy (TRT) typically decreases sperm count, it does not automatically render you infertile. Some men find they can still father children while on TRT. However, it's essential not to assume contraception isn't necessary simply because you're undergoing TRT.


Nevertheless, this approach carries risks because there's no guarantee of sustained fertility, and in many cases, TRT can reduce fertility unless supplemented with other medications to counteract this effect. While fertility often returns after discontinuing TRT, this is only sometimes the case, and the longer you use TRT, the higher the likelihood of fertility not fully recovering.


At Androgenix, we don't advocate this strategy. Nonetheless, it's worth noting that fertility levels may persist at sufficient levels for conception while on TRT.


2. Sperm Freezing And Storage For Future Use


Not all men starting testosterone replacement therapy (TRT) are currently focused on fathering children. Opting to freeze and store sperm serves as a valuable precaution, preserving fertility for later use. However, the cost associated with this option may deter some individuals.


It's important to note that sperm freezing and storage are recommended safeguards for all men, regardless of whether they are concurrently using medications to enhance or sustain fertility.


For those hesitant about the expense of storage, a third viable option exists, which is still advisable as a precautionary measure.


3. Utilize HCG And HMG Therapy To Preserve Fertility


HCG functions as a potent LH analogue, igniting the testes to reignite testosterone production within the body. This surge not only revitalizes sperm production but also triggers notable testicular growth. 


Supported by numerous studies, HCG stands as a pivotal aid in enhancing male fertility, particularly for individuals undergoing testosterone replacement therapy (TRT).


In a study involving 26 men supplementing injectable and transdermal testosterone with HCG, fertility remained intact throughout a follow-up period exceeding a year, suggesting sustained fertility beyond this duration.


In another study by Wenker et al. (2015) encompassing 49 men diagnosed with azoospermia, 47 individuals achieved normal sperm counts by the study's conclusion. Remarkably, even the 48th participant, who initially exhibited low sperm counts, reported a documented pregnancy during follow-up, underscoring the profound impact of HCG on male fertility restoration.


In a pivotal study by Kim et al. (2012), it was discovered that HCG administration preserved fertility even in the presence of concurrent testosterone supplementation—an especially critical finding for men undergoing testosterone replacement therapy (TRT).


Furthermore, Matsumoto et al. (2009) conducted a comprehensive investigation involving 36 men afflicted with severe hypogonadotropic hypogonadism characterized by low testosterone levels. Their research unequivocally demonstrated the efficacy of HCG in facilitating and sustaining fertility among this population.


In a seminal study conducted by Bouloux et al. (2002) involving 26 men grappling with severe hypogonadotropic hypogonadism, the efficacy of HCG in restoring sperm production to significant levels was underscored, marking a crucial advancement in fertility management.


Moreover, ongoing research continues to bolster the case for HCG utilization in fertility enhancement, with a burgeoning array of studies corroborating its efficacy. Beyond its fertility benefits, HCG proves invaluable in the realm of testosterone replacement therapy (TRT) by preserving vital hormone pathways that would otherwise be compromised during natural production suppression. This multifaceted role enhances men's overall well-being and yields notable improvements in lipid profiles, fostering a healthier physiological milieu.



How To Test Your Male Fertility


Testing for fertility in men can be done through various methods, and one convenient option is an at-home test kit available on our website. These tests offer excellent value and have been rigorously validated by the World Health Organization (WHO) for accuracy.


Our male fertility test kits provide a hassle-free solution, require no specialized training, and can be completed in just about 15 minutes. With the convenience of conducting the test at home, there's no need for potentially embarrassing clinic visits, ensuring utmost comfort and privacy throughout the process.



Where Can I Get HCG In The EU?


HCG used to be commonly utilized in the USA alongside TRT to maintain a man's fertility levels. However, it has become less common due to new regulations significantly increasing US costs. Clomid is now used as an alternative, though it is not as effective.


In the EU, it is becoming easier to access through specialized clinics. It is primarily available through specialist TRT providers and not typically through public health services for use in conjunction with TRT in men.


At Androgenix, we can assist eligible patients in achieving normal testosterone levels while maintaining excellent fertility, all at very competitive prices. This is made possible through a combination of innovative protocols, testosterone compounds, and HCG.



Conclusion


TRT is a remarkable therapy that, for many years, was primarily advised for older men or those with significantly low testosterone levels due to concerns about its impact on fertility.


Men considering this treatment had to consider the benefits while facing the possibility that they might not be able to father children after beginning the therapy.


Now, with advancements in medication such as HCG, there are viable options available that allow men to maintain their fertility while enhancing their prospects of starting a family in the future.


Reach out to us to discover more about initiating TRT and HCG treatment.



References


Patel, A. S., Leong, J. Y., Ramos, L., & Ramasamy, R. Testosterone is a contraceptive and should not be used in men who desire fertility.


McBride, J. A., & Coward, R. M. Recovery of spermatogenesis following testosterone replacement therapy or anabolic-androgenic steroid use.


Song, S., & Kim, D. S. Misuse of testosterone replacement therapy in infertile couples and influence on the infertility treatment program.


Desai, A., Yassin, M., Minhas, S., et al. Understanding and managing the suppression of spermatogenesis caused by testosterone replacement therapy (TRT) and anabolic–androgenic steroids (AAS).


El Meliegy, A., Motawi, A., & Abd El Salam, M. A. Systematic review of hormone replacement therapy in the infertile man.


Fink, J., Ide, H., & Horie, S. Management of male fertility in hypogonadal patients on testosterone replacement therapy.

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